Cocculus hirsutus: Molecular docking to identify suitable targets for hepatocellular carcinoma by in silico technique
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چکیده
منابع مشابه
Antimicrobial Activity of the Roots of Cocculus Hirsutus
Cocculus hirsutus Linn was studied for antimicrobial activity against Staphylococcus aureus, Echerchia coli, Pseudomonas aeruginosa and Salmonella typhi using agar disc-diffusion method. Petroleum ether extract, Ethanolic extract and Crude alkaloidal fraction were screened for the activity in various concentrations and zone of inhibitions were recorded. Results suggest that the Ethanolic extrac...
متن کاملPreliminary Phytochemical Studies on the Roots of Cocculus Hirsutus, Linn.
The roots of Cocculus hirsutus (Linn) Diels was analyzed for preliminary phytochemical studies including physical constant (total ash, acid soluble and insoluble ash and moisture content), extractive values in different solvents (petroleum ether, benzene, chloroform, methanol and water), and phytochemical tests. The plant is well reputed in traditional system of medicine, present studies will h...
متن کاملPrognostic molecular markers in hepatocellular carcinoma (Review article
Hepatocellular carcinoma (HCC) is the 5th commonest malignancy worldwide and is the third most common cause of cancer-related death. The prevalence is different in the world. The ability to predict patients at higher risk of recurrence and with a poor prognosis would help to guide surgical and chemotherapeutic treatment according to individual risk. As understanding of hepatocarcinogenesi...
متن کاملHepatocellular Carcinoma: Novel Molecular Targets in Carcinogenesis for Future Therapies
BACKGROUND Hepatocellular carcinoma is one of the most common and lethal malignant tumors worldwide. Over the past 15 years, the incidence of HCC has more than doubled. Due to late diagnosis and/or advanced underlying liver cirrhosis, only limited treatment options with marginal clinical benefit are available in up to 70% of patients. During the last decades, no effective conventional cytotoxic...
متن کاملUsing reverse docking to identify potential targets for ginsenosides
BACKGROUND Ginsenosides are the main ingredients of ginseng, which, in traditional Eastern medicine, has been claimed to have therapeutic values for many diseases. In order to verify the effects of ginseng that have been empirically observed, we utilized the reverse docking method to screen for target proteins that are linked to specific diseases. METHODS We constructed a target protein datab...
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ژورنال
عنوان ژورنال: Pharmacognosy Magazine
سال: 2016
ISSN: 0973-1296
DOI: 10.4103/0973-1296.185769